Yang Yu Selected Research

Phosphotransferases (Kinase)

1/2023	Deciphering the Shared and Specific Drug Resistance Mechanisms of Anaplastic Lymphoma Kinase via Binding Free Energy Computation.
12/2022	The Structure, Function and Regulation of Protein Tyrosine Phosphatase Receptor Type J and Its Role in Diseases.
1/2022	M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival.
1/2022	Resolvin D1 Alleviates Mechanical Allodynia via ALX/FPR2 Receptor Targeted Nod-like Receptor Protein 3/Extracellular Signal-Related Kinase Signaling in a Neuropathic Pain Model.
5/2021	TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers.
1/2021	Tian-Huang Formula, a Traditional Chinese Medicinal Prescription, Improves Hepatosteatosis and Glucose Intolerance Targeting AKT-SREBP Nexus in Diet-Induced Obese Rats.
10/2019	Small molecule inhibitor agerafenib effectively suppresses neuroblastoma tumor growth in mouse models via inhibiting ERK MAPK signaling.
1/2019	Antitumor effects of anlotinib in thyroid cancer.
3/2018	Combination of Luteolin and Solifenacin Improves Urinary Dysfunction Induced by Diabetic Cystopathy in Rats.
11/2017	Small molecule inhibitor regorafenib inhibits RET signaling in neuroblastoma cells and effectively suppresses tumor growth in vivo.

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Yang Yu Research Topics

Disease

436	Neoplasms (Cancer) 05/2024 - 12/2005
95	Inflammation (Inflammations) 05/2024 - 08/2007
94	Infections 04/2024 - 09/2002
86	Breast Neoplasms (Breast Cancer) 12/2023 - 12/2010
72	Neoplasm Metastasis (Metastasis) 01/2024 - 06/2003
42	Scoliosis 04/2023 - 12/2005
36	Fibrosis (Cirrhosis) 05/2024 - 04/2002
36	Colorectal Neoplasms (Colorectal Cancer) 02/2024 - 08/2013
35	Heart Failure 02/2024 - 09/2006
33	Carcinogenesis 12/2023 - 05/2009
32	Obesity 04/2024 - 12/2006
30	Hemorrhage 02/2024 - 02/2014
30	Wounds and Injuries (Trauma) 12/2023 - 10/2003
30	Carcinoma (Carcinomatosis) 01/2023 - 02/2010
29	Pain (Aches) 03/2024 - 07/2008
28	Stomach Neoplasms (Stomach Cancer) 04/2024 - 07/2011
28	Myocardial Infarction 01/2024 - 08/2007
28	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 01/2012
28	Cognitive Dysfunction 12/2023 - 12/2014
28	Hypoxia (Hypoxemia) 11/2023 - 04/2014
26	Body Weight (Weight, Body) 12/2023 - 09/2006
24	Insulin Resistance 02/2024 - 09/2011
24	Ovarian Neoplasms (Ovarian Cancer) 03/2023 - 07/2012
24	Atherosclerosis 01/2023 - 11/2009
23	Kyphosis 04/2024 - 11/2007
23	Hypertension (High Blood Pressure) 02/2024 - 08/2008
22	Sepsis (Septicemia) 01/2024 - 01/2009
21	Neuroinflammatory Diseases 04/2024 - 11/2014
20	Hepatocellular Carcinoma (Hepatoma) 01/2024 - 10/2011
20	COVID-19 03/2023 - 01/2020
19	Osteoporosis 10/2023 - 10/2013
19	Lung Neoplasms (Lung Cancer) 09/2023 - 02/2008
19	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 11/2012
18	Stroke (Strokes) 01/2024 - 05/2014
17	Hypersensitivity (Allergy) 03/2024 - 12/2006
17	Prostatic Neoplasms (Prostate Cancer) 03/2024 - 01/2011
17	Type 2 Diabetes Mellitus (MODY) 12/2023 - 07/2011
17	Glioma (Gliomas) 05/2023 - 02/2012
17	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2023 - 09/2013
17	Neuroblastoma 11/2022 - 01/2015
16	Ankylosing Spondylitis 01/2023 - 10/2012
15	Colitis 05/2024 - 10/2013
15	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2024 - 05/2009
15	Ischemia 12/2023 - 04/2002
15	Parkinson Disease (Parkinson's Disease) 12/2023 - 02/2008
15	Papillary Thyroid Cancer 01/2023 - 06/2006
14	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 01/2013
14	Lymphatic Metastasis 01/2024 - 06/2006
14	Reperfusion Injury 12/2023 - 11/2011
14	Virus Diseases (Viral Diseases) 12/2023 - 11/2007
14	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2022 - 10/2007
13	Liver Neoplasms (Liver Cancer) 01/2024 - 03/2005

Drug/Important Bio-Agent (IBA)

175	Proteins (Proteins, Gene)FDA Link 05/2024 - 09/2005
83	Biomarkers (Surrogate Marker)IBA 04/2024 - 08/2011
63	Messenger RNA (mRNA)IBA 03/2024 - 10/2003
55	CytokinesIBA 04/2024 - 08/2004
49	Long Noncoding RNAIBA 01/2024 - 01/2017
48	DNA (Deoxyribonucleic Acid)IBA 03/2024 - 07/2008
40	MicroRNAs (MicroRNA)IBA 04/2024 - 12/2010
36	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 11/2002
29	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2024 - 10/2007
27	Small Interfering RNA (siRNA)IBA 02/2024 - 03/2009
26	Therapeutic UsesIBA 01/2024 - 09/2005
26	EnzymesIBA 01/2024 - 10/2003
25	RNA (Ribonucleic Acid)IBA 12/2023 - 03/2012
25	HydrogenIBA 06/2021 - 01/2012
24	AntioxidantsIBA 12/2023 - 05/2010
24	Peptides (Polypeptides)IBA 10/2023 - 12/2006
21	LipidsIBA 02/2024 - 11/2009
21	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2023 - 11/2012
20	Anti-Bacterial Agents (Antibiotics)IBA 03/2024 - 09/2009
20	CholesterolIBA 02/2024 - 06/2007
18	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2024 - 06/2008
18	Hormones (Hormone)IBA 03/2024 - 04/2015
18	Cisplatin (Platino)FDA LinkGeneric 07/2023 - 06/2006
18	Phosphotransferases (Kinase)IBA 01/2023 - 10/2015
18	Insulin (Novolin)FDA Link 03/2022 - 12/2006
18	Angiotensin IIIBA 01/2021 - 10/2007
17	Amyloid (Amyloid Fibrils)IBA 04/2024 - 01/2014
17	Triglycerides (Triacylglycerol)IBA 03/2024 - 06/2007
17	Liposomes (Liposome)IBA 09/2023 - 01/2011
17	salicylhydroxamic acid (SHAM)IBA 01/2022 - 03/2008
16	Immune Checkpoint InhibitorsIBA 04/2024 - 02/2021
16	Interleukin-6 (Interleukin 6)IBA 03/2024 - 01/2012
15	LigandsIBA 02/2024 - 10/2012
15	IronIBA 12/2023 - 10/2006
14	Transcription Factors (Transcription Factor)IBA 02/2024 - 01/2014
13	CalciumIBA 05/2024 - 05/2014
13	LipopolysaccharidesIBA 12/2023 - 06/2012
13	Apolipoproteins E (ApoE)IBA 09/2023 - 11/2009
13	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 09/2006

Therapy/Procedure

181	Therapeutics 05/2024 - 07/2005
86	Drug Therapy (Chemotherapy) 02/2024 - 10/2007
45	Immunotherapy 05/2024 - 07/2008
30	Radiotherapy 01/2023 - 01/2012
25	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2024 - 03/2005
18	Osteotomy 01/2023 - 11/2007
15	Pedicle Screws 02/2024 - 02/2009
13	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2024 - 03/2015
13	Transplantation 01/2023 - 04/2002